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No specific dose adjustment advised when tofacitinib coadministered with potent CYP2C19 inhibitors; reduce tofacitinib dose if coadministered with each moderate CYP3A4 and powerful CYP2C19 inhibitors .When you pass up a dose, take it once you can. If it is almost time for your future dose, consider only that dose. Never acquire double or more doses

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